Effects of Prolonged Night Shifts on Salivary α-Amylase, Secretory Immunoglobulin, Cortisol, and Chromogranin A Levels in Nurses

نویسندگان

  • Yosuke Morita
  • Hideko Aida
  • Takuji Yamaguchi
  • Masakazu Azuma
  • Sennichi Suzuki
  • Nobuhiro Suetake
  • Takehiko Yukishita
  • Keiko Lee
  • Hiroyuki Kobayashi
چکیده

Prolonged night shift is associated with high burnout rate, but the physiological effects of a 16 h shift remain undetermined. Here we evaluated fatigue and stress via salivary assays to determine the correlation between stress and fatigue and prolonged night shifts. Twenty-five nurses (9 men, 16 women; 16 h night shift (n = 13), 8 h day shift (n = 12)) from Juntendo University Koshigaya Hospital were evaluated for four consecutive workdays separated by off days. Salivary samples were collected upon waking and before sleep on non-working days, before and after the day and night shifts, and before and after the break during the nocturnal schedule, and analyzed for levels of cortisol, chromogranin A, α-amylase activity and secretory immunoglobulin A (sIgA). On nonworking days, cortisol levels showed similar kinetic pattern in both nurses. On working days, daytime nurses’ cortisol levels showed normal circadian pattern throughout the shift. Night nurses’ cortisol levels at the beginning of the shift were comparable to that of the normal morning elevation. α-Amylase activity in the night shift nurses was higher than day shift nurses through each period. No significant differences in chromogranin A and sIgA levels were detected between day and night shift workers. A 16 h night shift may cause marked circadian misalignment in cortisol levels.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Salivary and serum chromogranin A and α-amylase in periodontal health and disease.

BACKGROUND Salivary stress-related biomarkers in connection with periodontal disease have not been extensively studied. In addition to cortisol as a well-known marker of stress loading, chromogranin A (CgA) and α-amylase (AA) are supposed to link the activity of the neuroendocrine system to local and systemic immune functions and to be related to periodontitis. This study aims to determine CgA ...

متن کامل

Correlation of α1-antitrypsin (A1AT), Complement component C5a and Secretory Immunoglobulin A (sIgA) with pulmonary complications; 20 years after sulfur mustard exposure, Sardasht-Iran Cohort Study

Background: Little is known about pulmonary complications induced by Sulfur Mustard (SM), as a chemical warfare agent,especially considering its long term effects. The present study was carried out to investigate the association of α1-antitrypsin(A1AT), Complement component C5a, and Secretory Immunoglobulin A (sIgA) with long-term pulmonary complications on SMexposedindividuals, 20 years after ...

متن کامل

Assessment of salivary human herpesvirus-6 and immunoglobulin a levels in nurses working shifts.

PURPOSE The purpose of the present study was to assess whether salivary human herpesvirus (HHV)-6 acted as a new sensitive stress marker, providing a reliable indicator of stress among shift work nurses. Salivary HHV-6, immunoglobulin (Ig) A and mood states were compared among nurses who worked day shifts only and nurses who worked different numbers of night shifts. METHODS Participants inclu...

متن کامل

The application of Reiki in nurses diagnosed with Burnout Syndrome has beneficial effects on concentration of salivary IgA and blood pressure.

This study aimed to investigate the immediate effects of the secretory immunoglobulin A (sIgA), α-amylase activity and blood pressure levels after the application of a Reiki session in nurses with Burnout Syndrome. A randomized, double-blind, placebo-controlled, crossover design was conducted to compare the immediate effects of Reiki versus control intervention (Hand-off sham intervention) in n...

متن کامل

Salivary mental stress proteins.

Of the major diagnostic specimen types, saliva is one of the most easily collected. Many studies have focused on the evaluation of salivary proteins secreted by healthy people and patients with various diseases during responses to acute mental stress. In particular, such studies have focused on cortisol, α-amylase, chromogranin A (CgA), and immunoglobulin A (IgA) as salivary stress markers. Eac...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2014